Non-invasive cardiac imaging is less costly, more time efficient and less invasive than the conventional angiogram. For these reasons, many have concluded that non-invasive cardiac imaging could replace cardiac catheterization as the standard test for heart blockages. Radiology groups, cardiology groups and other stakeholders such as hospitals should consider how they can work together to offer non-invasive cardiac imaging successfully in light of the regulatory issues involved and the impact this new tool may have on the core business models for the diagnostic component of cardiac care.